We track 60 players in 2022 Topps baseball cards including Mike Trout, Shohei Ohtani, Fernando Tatis Jr., Ronald Acuna Jr., Vladimir Guerrero Jr., Juan Soto, Bryce Harper, Mookie Betts, Wander Franco and Brandon Marsh. Sports Card Investor also tracks a total of 543 card in the 2022 Topps set. The top trending card in 2022 Topps is currently Wander Franco's 2022 Topps Platinum.